Sample size calculations need to be adequate and parsimonious
نویسندگان
چکیده
منابع مشابه
Statistics: An introduction to sample size calculations
One crucial aspect of study design is deciding how big your sample should be. If you increase your sample size you increase the precision of your estimates, which means that, for any given estimate / size of effect, the greater the sample size the more “statistically significant” the result will be. In other words, if an investigation is too small then it will not detect results that are in fac...
متن کاملDo Antibiotic Beads Need to be Removed?
Background: Polymethylmethacrylate antibiotic impregnated beads can be an effective treatment for chronicosteomyelitis or an adjuvant in the treatment of open fractures. It remains unclear however whether the beads causelong-term adverse events if not removed. The purpose of this study was to determine if removal of antibiotic beads wasrequired in order to avoid long term comp...
متن کاملSample size calculations: should the emperor's clothes be off the peg or made to measure?
Conventional wisdom dictates that it is unethical to conduct a study that is so large that excess numbers of patients are exposed or so small that clinically important changes cannot be detected. This implies that there is some optimal sample size that can be calculated using statistical theory and information from previous research. But the choice of sample size is usually a compromise between...
متن کاملSample-Size Calculations for Cohen's Kappa
In recent years, researchers in the psychosocial and biomedical sciences have become increasingly aware of the importance of sample-size calculations in the design of research projects. Such considerations are, however, rarely applied for studies involving agreement of raters. Published results on this topic are limited and generally provide rather complex formulas. In addition, they generally ...
متن کاملSample size calculations for randomized controlled trials.
Most informed consent documents for randomized controlled trials implicitly or explicitly promise the prospective participant that the trial has a reasonable chance of answering a medically important question. The medical literature, however, is replete with descriptions of trials that provided equivocal answers to the questions they addressed. Papers describing the results of such studies may ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Epidemiology
سال: 2019
ISSN: 0895-4356
DOI: 10.1016/j.jclinepi.2018.11.018